Publications
2021
Ruijgrok PV, Ghosh RP, Zemsky S, Nakamura M, Gong R, Ning L, Chen R, Vachharajani VT, Chu AE, Anand N, Eguchi RR, Huang P-S, Lin MZ, Alushin GM, Liphardt JT, and Bryant Z "Optical control of fast and processive engineered myosins in vitro and in living cells." Nat Chem Biol 2021
Pubmed | PDF | Nature Chemical Biology
Zhang R, Redford, S, Ruijgrok PV, Kumar K, Mozaffari A, Zemsky S, Dinner AR, Vitelli V, Bryant Z, Gardel M, and de Pablo JJ "Spatiotemporal control of liquid crystal structure and dynamics through activity patterning." Nat Mater 2021
Pubmed | PDF | Nature Materials
Colen J, Han M, Zhang R, Redford SA, Lemma LM, Morgan L, Ruijgrok PV, Adkins R, Bryant Z, Dogic Z, Gardel ML, de Pablo JJ, Vitelli V "Machine learning active-nematic hydrodynamics." Proc Natl Acad Sci U S A 2021
Pubmed | PDF | PNAS
Galvin CJ, Liu KN, Kennard AS, Tembulkar SH, Dunlap A, Large TAG, Pham T, Le D, Alvarez-Buylla A, Nguyen H, Ponce E, Tran S, Nguyen N, Ngo C, Tran C, Huynh G, Allamandola P, and Bryant Z "Curiosity-based biophysics projects in a high school setting with graduate student mentorship." The Biophysicist 2021
PDF | The Biophysicist
2020
Ivanov IE, Wright AV, Cofsky JC, Aris KDP, Doudna JA, and Bryant Z "Cas9 interrogates DNA in discrete steps modulated by mismatches and supercoiling." Proc Natl Acad U S A 2020
Pubmed | PDF | PNAS
Hobson MJ, Bryant Z, and Berger JM "Modulated control of DNA supercoiling balance by the DNA-wrapping domain of bacterial gyrase" Nucleic Acids Res 2020
Pubmed | PDF | Nucleic Acids Research
Iino R, Kinbara K, and Bryant Z "Introduction: Molecular motors." Chem Rev 2020
Pubmed | PDF | Editorial
2019
Ivanov IE and Bryant Z "Multi-parameter measurements of conformational dynamics in nucleic acids and nucleoprotein complexes." Methods 2019
Pubmed | PDF | Methods
2018
Acharya BR, Nestor-Bergmann A, Liang X, Gupta S, Duszyc K, Gauquelin E, Gomez GA, Budnar S, Marcq P, Jensen OE, Bryant Z, and Yap AS "A mechanosensitive RhoA pathway that protects epithelia against acute tensile stress." Dev Cell 2018
Pubmed | PDF | Developmental Cell
Basu A, Hobson M, Lebel P, Fernandes LE, Tretter E, Berger JM, and Bryant Z Dynamic coupling between conformations and nucleotide states in DNA gyrase. Nat Chem Biol 2018
Pubmed | PDF | Nature Chemical Biology
Kaplan L, Ierokomos A, Chowdary P, Bryant Z, and Cui B "Rotation of endosomes demonstrates coordination of molecular motors during axonal transport." Sci Adv 2018
Pubmed | PDF | Science Advances
Ivanov IE, Lebel P, Oberstrass FC, Starr CH, Parente AC, Ierokomos A, and Bryant Z "Multimodal measurements of single-molecule dynamics using FluoRBT." Biophys J 2018
Pubmed | PDF | Biophysical Letter
Omabegho T, Gurel PS, Cheng CY, Kim LY, Ruijgrok PV, Das R, Alushin GM, and Bryant Z "Controllable molecular motors engineered from myosin and RNA." Nat Nanotechnol 2018
Pubmed | PDF | Letter
2017
Ivanov IE, Lebel P, Oberstrass FC, Starr CH, Parente AC, Ierokomos A, and Bryant Z "Multimodal measurements of single-molecule dynamics using FluoRBT." Biophys J 2017
Pubmed | PDF | Biophysical Journal
Gurel PS, Kim LY, Ruijgrok PV, Omabegho T, Bryant Z, and Alushin GM "Cryo-EM structures reveal specialization at the myosin VI-actin interface and a mechanism of force sensitivity." eLife 2017
Pubmed | eLife
Omabegho T, Gurel PS, Cheng CY, Kim LY, Ruijgrok PV, Das, R, Alushin GM, and Bryant Z "Controllable molecular motors engineered from myosin and RNA." Nat Nanotechnol 2017
Pubmed | PDF | Nature Nanotechnology
2016
Basu A, Parente AC, and Bryant Z "Structural dynamics and mechanochemical coupling in DNA gyrase." J Mol Biol 2016
Pubmed | PDF
2014
Nakamura M, Chen L, Howes SC, Schindler TD, Nogales E, and Bryant Z “Remote control of myosin and kinesin motors using light-activated gearshifting.” Nat Nanotechnol 2014
Pubmed | PDF | News and Views
Lebel P, Basu A, Oberstrass FC, Tretter EM, and Bryant Z "Gold rotor bead tracking for high-speed measurements of DNA twist, torque, and extension." Nat Methods 2014
Pubmed | Nature Methods | PDF
Schindler TD, Chen L, Lebel P, Nakamura M, and Bryant Z "Engineering myosins for long-range transport on actin filaments." Nat Nanotechnol 2014
Pubmed | PDF | Editorial | News and Views
2013
Cipriano DJ, Jung J, Vivona S, Fenn TD, Brunger AT, and Bryant Z "Processive ATP-driven substrate disassembly by the N-ethylmaleimide-sensitive factor (NSF) molecular machine." J Biol Chem 2013
Pubmed | PDF
Oberstrass FC, Fernandes LE, Lebel P, and Bryant Z "Torque Spectroscopy of DNA: Base-Pair Stability, Boundary Effects, Backbending, and Breathing Dynamics." Phys Rev Lett 2013
Pubmed | PDF | Physics Highlight
2012
Bryant Z, Oberstrass FC, and Basu A "Recent developments in single-molecule DNA mechanics." Curr Opin Struct Biol 2012
Pubmed | PDF
Basu A, Schoeffler AJ, Berger JM, and Bryant Z "ATP binding controls distinct structural transitions of E. Coli DNA gyrase in complex with DNA." Nat Struct Mol Biol 2012
Pubmed | PDF | Cover
Oberstrass FC, Fernandes LE, and Bryant Z "Torque measurements reveal sequence-specific structural transitions in supercoiled DNA." Proc Natl Acad Sci USA 2012
Pubmed | PDF
Chen L, Nakamura M, Schindler TD, Parker D, and Bryant Z "Engineering controllable bidirectional molecular motors based on myosin." Nat Nanotechnol 2012
Pubmed | PDF | News and Views
2011
Elting MW, Bryant Z, Liao J-C, and Spudich JA "Detailed tuning of structure and intramolecular communication are dispensable for processive motion of myosin VI." Biophys J 2011
Pubmed | PDF
2010
Dunn AR, Chuan P, Bryant Z, and Spudich JA "Contribution of the myosin VI tail domain to processive stepping and intramolecular tension sensing." Proc Natl Acad Sci USA 2010
Pubmed | PDF
2009
Parker D, Bryant Z, and Delp S. "Coarse-grained structural modeling of molecular motors using multibody dynamics." Cellular and Molecular Bioengineering 2009
Pubmed | PDF
Liao JC, Elting MW, Spudich JA, and Bryant Z "Engineered myosin VI motors reveal minimal structural determinants of directionality and processivity." J Mol Biol 2009
Pubmed | PDF
2007
Nöllmann M, Stone MD, Bryant Z, Gore J, Crisona NJ, Hong SC, Mitelheiser S, Maxwell A, Bustamante C, and Cozzarelli NR "Multiple modes of Escherichia coli DNA gyrase activity revealed by force and torque." Nat Struct Mol Biol 2007;14: 4: 264-71
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Bryant Z, Altman D, and Spudich JA "The power stroke of myosin VI and the basis of reverse directionality." Proc Natl Acad Sci U S A 2007; 104: 3: 772-7
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2006
Gore J, Bryant Z, Nöllmann M, Le MU, Cozzarelli NR, and Bustamante C "DNA overwinds when stretched." Nature 2006; 442: 7104: 836-9
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Gore J, Bryant Z, Stone MD, Nöllmann M, Cozzarelli NR, and Bustamante C "Mechanochemical analysis of DNA gyrase using rotor bead tracking." Nature 2006; 439: 7072: 100-4
Pubmed | PDF
2003
Bryant Z, Stone MD, Gore J, Smith SB, Cozzarelli NR, and Bustamante C "Structural transitions and elasticity from torque measurements on DNA." Nature 2003; 424: 6946: 338-41
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Stone MD, Bryant Z, Crisona NJ, Smith SB, Vologodskii A, Bustamante C, and Cozzarelli NR "Chirality sensing by Escherichia coli topoisomerase IV and the mechanism of type II topoisomerases." Proc Natl Acad Sci U S A 2003; 100: 15: 8654-9
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Bustamante C, Bryant Z, and Smith SB "Ten years of tension: single-molecule DNA mechanics." Nature 2003; 421: 6921: 423-7
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2000
Bryant Z, Pande VS, and Rokhsar DS "Mechanical unfolding of a beta-hairpin using molecular dynamics." Biophys J 2000; 78: 2: 584-9
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1999
Bryant Z, Subrahmanyan L, Tworoger M, LaTray L, Liu CR, Li MJ, van den Engh G, and Ruohola-Baker H "Characterization of differentially expressed genes in purified Drosophila follicle cells: toward a general strategy for cell type-specific developmental analysis." Proc Natl Acad Sci U S A 1999; 96: 10: 5559-64
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Tworoger M, Larkin MK, Bryant Z, and Ruohola-Baker H "Mosaic analysis in the drosophila ovary reveals a common hedgehog-inducible precursor stage for stalk and polar cells." Genetics 1999; 151: 2: 739-48
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1997
Clegg NJ, Frost DM, Larkin MK, Subrahmanyan L, Bryant Z, and Ruohola-Baker H "maelstrom is required for an early step in the establishment of Drosophila oocyte polarity: posterior localization of grk mRNA." Development 1997; 124: 22: 4661-71
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